The Situation: Initiatives that begin with a product focus often fail. Yet, this happens time and again in the life sciences industry. The clinical operations group of a life sciences company initiated a clinical trial management system (CTMS) project without the participation of several key stakeholder groups. They engaged a CTMS vendor to write their requirements and then selected a solution based on each vendor’s standard demonstrations in which the vendor controlled the environment and the demo content. Shortly thereafter, senior management stopped the project due to insufficient due diligence, limited adherence to IT standards, and lack of confidence in the approach. ResultWorks was asked to assess the project and to create a new strategy for the CTMS effort.